Tramadol sold as MDMA caps
Yellow and green capsules that were acquired as ‘MDMA’ were tested and found to contain only
tramadol.

What is tramadol?
Tramadol is a synthetic opioid which is a central nervous system depressant/painkiller.
It’s a very different substance from MDMA, which is a stimulant/empathogen.
Combining tramadol with drugs that affect serotonin can cause serotonin toxicity, a serious
medical emergency.
This includes:
- MDMA
- Methamphetamine
- Cathinones like mephedrone
- Antidepressants (SSRIs, SNRIs, MAOIs, TCAs)
Combining tramadol with other depressants (e.g. alcohol, benzodiazepines) can cause respiratory depression and overdose.
Signs of serotonin toxicity include:
- Agitation or confusion
- Heavy sweating, feeling very hot
- Shaking, muscle twitching or stiff muscles
- Rapid heart rate or chest pain
- Loss of consciousness or seizures
What to do:
- Call triple zero ‘000’
- Keep the person cool
- Place in the recovery position
- Stay with the person until help arrives
Signs of opioid overdose:
- Slow, shallow or stopped breathing
- Snoring, choking or gurgling sounds
- Unresponsive or hard to wake
- Blue (or grey) lips and fingernails
- Pale, cold or clammy skin
- Slow or irregular pulse
What to do:
- Call triple zero ‘000’
- Give naloxone
- Rescue breaths if not breathing
- Place in the recovery position
- Give more naloxone if no response
- Stay until help arrives
Harm reduction tips
- Test your drugs – Even if you think you know what you have, it’s best to test and be sure
- Carry naloxone – Opioids can be in any substance. Naloxone reverses opioid overdose, is legal and widely available
- Avoid mixing drugs – Tramadol can interact with prescription medicines and other drugs
- Avoid using alone – Use with people you trust who can help if something goes wrong
- Start low, go slow – Start with a small amount, don’t redose until you know what to expect
Call triple zero ‘000’ immediately If you or someone else experience adverse effects.
Get your drugs tested!
Only a very small amount is needed – approximately 10mg (0.01g)
Victorian Pill Testing Service
95 Brunswick Street
Fitzroy VIC
Call: 1800 762 844
www.vicpilltesting.org.au




