There has been a recent case of N-pyrrolidino protonitazene (also known as protonitazepyne) and protonitazene detected in toxicology and tablet samples, in South-East Queensland.

N-pyrrolidino protonitazene and protonitazene are very strong synthetic opioids that work like heroin or fentanyl and can produce life-threatening toxicity in small amounts. The appearance of the sample is a pale yellow, bear shaped pressed pill marked Y.

Toxic Effects

The toxic effects of N-pyrrolidino protonitazene and protonitazene are similar to other potent synthetic opioids and include:

• Extreme drowsiness or the person may even be impossible to wake (‘on the nod’)
• Small (‘pin point’) pupils
• Slowed or obstructed breathing
• Respiratory failure that can lead to death
• Blue or purple coloured skin (cyanosis), usually starting on lips and fingers

These effects should respond to naloxone, and it should be used if available. More information on accessing Naloxone below.

Information and Advice

Queensland Health advises that if you or someone you know suspects you have this substance, do not consume instead dispose of it safely. Seek medical attention immediately if you or someone you know experiences any toxic effects following drug use.

Harm reduction information

Naloxone is available for free from registered pharmacies and services through the national Take Home Naloxone program.

For help

• Call Triple Zero (000) for emergency assistance
• Go to your nearest emergency department
• Call the Queensland Poisons Information Centre (13 11 26)
• ADIS 24/7 Alcohol and Drug support (1800 177 833 or www.adis.health.qld.gov.au)
• Peer Qnect confidential telephone peer support (1800 175 889)