Potent dissociative ‘O-PCE’(deschloro-N-ethyl-ketamine) found in ketamineFebruary 13, 2026VICDissociatives Ketamine Ketamine analoguesTwo separate samples expected to be ketamine were found to contain O-PCE. What is O-PCE? O-PCE (deschloro-N-ethyl-ketamine)-a ketamine analogue, is a dissociative and hallucinogen that is most commonly mis-sold as ketamine. Dissociatives are drugs that make you feel disconnected from your body or surroundings. Ketamine analogues copy ketamine’s chemical makeup but can produce different effects, including stronger dissociation or hallucinatoryRead notification
2-oxo-PCE found in ‘ketamine’ sampleAugust 27, 2025ACTDissociatives KetamineA WHITE POWDER SAMPLE expected to contain ketamine was found to contain 2-oxo-PCE (O-PCE, N-ethyldeschloroketamine) instead. What does this mean? 2-oxo-PCE is a psychoactive substance that has dissociative effects, similar to but more potent than ketamine. Effects of 2-oxo-PCE can include psychedelic experiences, which are described as more potent and stimulating and much longer-acting than ketamine (approx. 3- 6 hoursRead notification
Potent dissociative ‘O-PCE’ sold as methamphetamine or MDMAMay 30, 2025VICAmphetamines Dissociatives Empathogens MDMA/Ecstasy StimulantsO-PCE is a potent and long-acting ‘dissociative’ O-PCE (deschloro-N-ethyl-ketamine) is a dissociative/hallucinogen that is most commonly mis-sold as “extra strong ketamine”. Dissociatives are drugs that make you feel disconnected from your body or surroundings. Compared with ketamine, O-PCE appears to be more potent and stimulating and is much longer-acting (3-6 hours compared with 30-60 minutes). People who have used O-PCE say the dissociation is deeper and more disorienting, with more intenseRead notification
3-Hydroxy-PCP sold as ketamineNovember 11, 2022VICDissociatives KetamineNote: White powder containing ‘3-Hydroxy-PCP’ is being sold as ketamine in Victoria. 3-HO-PCP is a “dissociative” drug that takes longer to have an effect than ketamine, but is more potent and unpredictable A dissociative increases feelings of ‘distance from reality’, but also has other effects. Not much is known about 3-HO-PCP, but its effects appear to include unconsciousness, raised bloodRead notification
2-FLUORO-2-OXO-PCE found in ketamine samplesSeptember 20, 2022ACTDissociatives KetamineYellowish white powder mixed with crystalline chunks repeatedly presented as ketamine and found to contain the new psychoactive substance 2-FLUORO-2-OXO-PCE instead. What is 2-FLUORO-2-OXO-PCE? A new synthetic ketamine derivative that has not been studied yet so information can’t be provided on short or long term effects or safety – we don’t know about duration, harmful dose levels or interactions withRead notification